{"id":8623,"date":"2020-06-22T12:01:56","date_gmt":"2020-06-22T12:01:56","guid":{"rendered":"https:\/\/cytomel-t3.com\/rozdil-mezi-t3-a-t4\/"},"modified":"2025-04-28T13:15:23","modified_gmt":"2025-04-28T13:15:23","slug":"rozdil-mezi-t3-a-t4","status":"publish","type":"page","link":"https:\/\/cytomel-t3.com\/cs\/rozdil-mezi-t3-a-t4\/","title":{"rendered":"Rozd\u00edl mezi T3 a T4"},"content":{"rendered":"

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Rozd\u00edl mezi T3 a T4<\/h1>\n<\/div>\n

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\u00davod<\/strong><\/h2>\n

Na krku, t\u011bsn\u011b pod „ohryzkem“, se nach\u00e1z\u00ed org\u00e1n ve tvaru mot\u00fdla. Tento org\u00e1n se naz\u00fdv\u00e1\u0161t\u00edtn\u00e1 \u017el\u00e1za<\/a>. Tato \u017el\u00e1za je zodpov\u011bdn\u00e1 za produkci dvou velmi d\u016fle\u017eit\u00fdch hormon\u016f, kter\u00e9 ovliv\u0148uj\u00ed metabolismus t\u011bla. Tyto hormony \u0161t\u00edtn\u00e9 \u017el\u00e1zy se zjednodu\u0161en\u011b naz\u00fdvaj\u00ed T3 a T4. <\/p>\n

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Co je to T3 a T4?<\/strong><\/h2>\n

T3 je zn\u00e1m\u00fd jako„trijodtyronin“,<\/a> zat\u00edmco T4 se naz\u00fdv\u00e1 „tyroxin“. Oba hormony \u0161t\u00edtn\u00e9 \u017el\u00e1zy jsou vytv\u00e1\u0159eny \u0161t\u00edtnou \u017el\u00e1zou, ale T4 je p\u0159edev\u0161\u00edm prekurzorov\u00fd hormon, co\u017e znamen\u00e1, \u017ee je hlavn\u00edm hormonem, kter\u00fd je vytv\u00e1\u0159en \u0161t\u00edtnou \u017el\u00e1zou. <\/p>\n

P\u0159i produkci tohoto hormonu je \u0161t\u00edtn\u00e1 \u017el\u00e1za do zna\u010dn\u00e9 m\u00edry z\u00e1visl\u00e1 na jodu dostupn\u00e9m v konzumovan\u00fdch potravin\u00e1ch. Oba hormony jsou sice zodpov\u011bdn\u00e9 za regulaci rychlosti metabolismu v t\u011ble, ale hormon \u0161t\u00edtn\u00e9 \u017el\u00e1zy<\/a> trijodtyronin (T3) je pova\u017eov\u00e1n za v\u00fdrazn\u011b aktivn\u011bj\u0161\u00ed hormon v t\u011ble. <\/p>\n

Trijodtyronin (T3) snadno pronik\u00e1 do bun\u011bk t\u011bla, proto\u017ee prakticky v\u0161echny lidsk\u00e9 bu\u0148ky maj\u00ed receptory \u0161t\u00edtn\u00e9 \u017el\u00e1zy. I kdy\u017e je T3 velmi \u017eivou formou hormonu \u0161t\u00edtn\u00e9 \u017el\u00e1zy, je t\u0159eba \u0159\u00edci, \u017ee kdy\u017e \u0161t\u00edtn\u00e1 \u017el\u00e1za produkuje hormony, p\u0159ibli\u017en\u011b 80 % poch\u00e1z\u00ed ve form\u011b T4, zat\u00edmco pouze 20 % hormon\u016f generovan\u00fdch \u017el\u00e1zou je ve skute\u010dnosti T3. <\/p>\n

Pokud m\u00e1 jedinec pot\u00ed\u017ee s tvorbou dostate\u010dn\u00e9ho mno\u017estv\u00ed hormon\u016f \u0161t\u00edtn\u00e9 \u017el\u00e1zy, m\u016f\u017ee b\u00fdt zapot\u0159eb\u00ed syntetick\u00fd hormon stimuluj\u00edc\u00ed \u0161t\u00edtnou \u017el\u00e1zu nebo TSH, jako je cytomel T3, kter\u00fd pom\u016f\u017ee stimulovat \u0161t\u00edtnou \u017el\u00e1zu k tvorb\u011b dostate\u010dn\u00e9ho mno\u017estv\u00ed hormon\u016f T4 a v\u017edy tak\u00e9 T3.<\/p>\n

Za p\u0159em\u011bnu T4 na T3 je zodpov\u011bdn\u00e1 chemick\u00e1 l\u00e1tka zn\u00e1m\u00e1 jako jodtyronin dejodin\u00e1za a tento proces p\u0159em\u011bny prob\u00edh\u00e1 p\u0159ev\u00e1\u017en\u011b v j\u00e1trech. P\u0159esto\u017ee ka\u017ed\u00e1 bu\u0148ka v t\u011ble je \u010d\u00e1ste\u010dn\u011b schopna t\u00e9to p\u0159em\u011bny, ale v r\u016fzn\u00e9 m\u00ed\u0159e. <\/p>\n

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Hlavn\u00ed rozd\u00edly mezi trijodtyroninem (T3) a tyroxinem (T4)<\/strong><\/h2>\n

Jak ji\u017e bylo zm\u00edn\u011bno, trijodtyronin je hlavn\u00edm hormonem \u0161t\u00edtn\u00e9 \u017el\u00e1zy. Hormon T3 je zn\u00e1m\u00fd jako katalyz\u00e1tor, kter\u00fd aktivn\u011b ovliv\u0148uje lidskou fyziologii r\u016fzn\u00fdmi zp\u016fsoby. T3 je nap\u0159\u00edklad zodpov\u011bdn\u00fd <\/a>p\u0159edev\u0161\u00edm za: <\/p>\n